IMMUNOTOXICOLOGY - 2017/8

Module code: APTM015

Module provider

School of Biosciences and Medicine

Module Leader

BAILEY I Dr (Biosc & Med)

Number of Credits

15

ECTS Credits

7.5

Framework

FHEQ Level 7

JACs code

B220

Module cap (Maximum number of students)

N/A

Module Availability

Year long

Overall student workload

Independent Study Hours: 120

Lecture Hours: 30

Assessment pattern

Assessment type Unit of assessment Weighting
Coursework COURSEWORK 100

Alternative Assessment

N/A

Prerequisites / Co-requisites

Module overview

An understanding of immunotoxicology is important for all areas of toxicology including consumer products, pharmaceuticals, agrochemicals, occupational exposure to chemicals and exposure to environmental pollutants. This module presents an overview of the types of reaction which occur with the immune system and the ways in which these are manifested in different tissues.

Module aims

Learning outcomes

Attributes Developed
1 Understand the basic functioning of the components of the immune system and how they interact in immune defence
2 Understand how toxic agents exert effects on the immune system and the basis of testing for immunotoxicity

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content



Introduction to immunotoxicity


Pathological evaluation of lymphoid tissue


Immune function testing and host resistance assays


Evaluation of immunotoxicity in humans


Human immunotoxins


Mechanisms of chemical-induced allergy


Approaches to investigation of contact sensitisation


Allergic contact dermatitis in man


Food allergy


Mechanisms of autoimmunity


Complement activation in drug immunotoxicity


Induced autoimmunity in man


Drug-induced hepatitis


Approaches to investigation of respiratory sensitisation


Occupational respiratory allergy in man


Asthma - aetiology and approaches to treatment


Immunotoxicity of organotins


Alternative methodologies


Methods of Teaching / Learning

The learning and teaching strategy is designed to:


Develop advanced knowledge and critical evaluation of issues arising in clinical trials and good clinical practice and procedures
Demonstrate skills in the application of knowledge, in self-direction and originality in tackling and solving problems in line with the learning outcomes


The learning and teaching methods include:



Lectures and seminars (24 hours)


Class discussion, tutorials and syndicate exercise (6 hours)



This is an intensive 4 day (09:00 – 17:00 each day) residential taught modules

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate


advanced knowledge and critical evaluation of issues arising in clinical trials and in good clinical practice
skills in the application of knowledge, in self-direction and originality in tackling and solving problems in line with the learning outcomes


 

Thus, the summative assessment for this module consists of:


2,000 word home assignment


 

Formative assessment and feedback


Class discussion
Module feedback session during module delivery

Reading list

Reading list for IMMUNOTOXICOLOGY : http://aspire.surrey.ac.uk/modules/aptm015

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.