Module code: APTM015

Module provider

School of Biosciences and Medicine

Module Leader

BAILEY I Dr (Biosc & Med)

Number of Credits


ECT Credits



FHEQ Level 7

JACs code


Module cap (Maximum number of students)


Module Availability

Year long

Overall student workload

Independent Study Hours: 120

Lecture Hours: 30

Assessment pattern

Assessment type Unit of assessment Weighting
Coursework COURSEWORK 100

Alternative Assessment


Prerequisites / Co-requisites

Module overview

An understanding of immunotoxicology is important for all areas of toxicology including consumer products, pharmaceuticals, agrochemicals, occupational exposure to chemicals and exposure to environmental pollutants. This module presents an overview of the types of reaction which occur with the immune system and the ways in which these are manifested in different tissues.

Module aims

Learning outcomes

Attributes Developed
Understand the basic functioning of the components of the immune system and how they interact in immune defence
Understand how toxic agents exert effects on the immune system and the basis of testing for immunotoxicity

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content

Module Content ¿ Introduction to immunotoxicity ¿ Pathological evaluation of lymphoid tissue ¿ Immune function testing and host resistance assays ¿ Evaluation of immunotoxicity in humans ¿ Human immunotoxins ¿ Mechanisms of chemical-induced allergy ¿ Approaches to investigation of contact sensitisation ¿ Allergic contact dermatitis in man ¿ Food allergy ¿ Mechanisms of autoimmunity ¿ Complement activation in drug immunotoxicity ¿ Induced autoimmunity in man ¿ Drug-induced hepatitis ¿ Approaches to investigation of respiratory sensitisation ¿ Occupational respiratory allergy in man ¿ Asthma - aetiology and approaches to treatment ¿ Immunotoxicity of organotins ¿ Alternative methodologies

Methods of Teaching / Learning

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate

advanced knowledge and critical evaluation of issues arising in clinical trials and in good clinical practice
skills in the application of knowledge, in self-direction and originality in tackling and solving problems in line with the learning outcomes


Thus, the summative assessment for this module consists of:

2,000 word home assignment


Formative assessment and feedback

Class discussion
Module feedback session during module delivery

Reading list

Reading list for IMMUNOTOXICOLOGY :

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.