BIOCHEMISTRY - ENZYMES AND METABOLISM - 2017/8

Module code: BMS2035

Module provider

School of Biosciences and Medicine

Module Leader

THUMSER AE Dr (Biosc & Med)

Number of Credits

15

ECT Credits

7.5

Framework

FHEQ Level 5

JACs code

C700

Module cap (Maximum number of students)

N/A

Module Availability

Semester 1

Overall student workload

Workshop Hours: 2

Independent Study Hours: 115

Lecture Hours: 28

Assessment pattern

Assessment type Unit of assessment Weighting
School-timetabled exam/test ON-LINE MCQ TEST 1 (20 MINS; 20 QUESTIONS) 12
School-timetabled exam/test ON-LINE MCQ TEST 2 (20 MINS; 20 QUESTIONS) 13
School-timetabled exam/test ON-LINE MCQ TEST 3 (20 MINS; 20 QUESTIONS) 12
School-timetabled exam/test ON-LINE MCQ TEST 4 (20 MINS; 20 QUESTIONS) 13
Examination 1 HOUR EXAMINATION (TWO SHORT ESSAYS) 50

Alternative Assessment

Not Applicable.

Prerequisites / Co-requisites

Pre-requisites: BMS1041 Biochemistry – A Conceptual Overview

Module overview

This module will cover two broad topics, namely Metabolism in Health & Disease (Dr Alfred Thumser, Dr Ian Bailey) and Cell Signalling (Dr Ian Bailey)

Module aims

Critically assess aspects of glucose and lipid metabolism

Discuss metabolic diseases in conjunction with metabolic pathways

Explain the concept of intracellular signalling pathways and its importance in cell function

Demonstrate the importance of protein phosphorylation in metabolic regulation.

Provide understanding on the surface and intracellular receptors and their major activated intracellular signalling pathways in health and disease

Discuss the importance of cellular signalling pathways in regulating gene transcription in health and disease

Learning outcomes

Attributes Developed
Define and describe glucose homeostasis ad control of glucose metabolism KC
Define and describe glucose metabolism in disease e.g. diabetes KC
Define and describe fatty acid metabolism, i.e. b-oxidation and synthesis KC
Define and describe the major plasma membrane and nuclear receptors KC
Descibe the intracellular signalling pathways activated by major plasma membrane and nuclear receptors and their role in controlling gene transcription in health and disease KC

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content

Indicative content includes:


Diabetes
Metabolic control of glycolysis and gluconeogenesis
Pentose phosphate pathway
Fatty acid β-oxidation and synthesis
Cell signalling
G-protein coupled receptors
Enzyme linked receptors
Ion channel receptors
Nuclear receptors
Tyrosine kinase associated receptors, e.g. JAK/STAT pathway (self-study; to be advised)
Receptor serine-threonine, TGFbeta receptor (self-study; to be advised)

Methods of Teaching / Learning

The learning and teaching methods include:


Lectures
Tutorials
“Think-pair-share” [formative]
Small-group essay workshops [formative]



 

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate critical thinking and understanding of the taught topics

Thus, the assessments for this module consist of:


MCQ tests 1 & 2 (topics taught by Dr Alfred Thumser), 3 & 4 (topics taught by Dr Ian Bailey)
Final exam (one hour; two short essays; the exam will be in two sections (AET & IB) and candidates should attempt one question from each section; three essay questions per section ; linked to all Learning Outcomes)


Formative assessment and feedback:


Generic in-class post-MCQ feedback
Peer-to-peer feedback in small-group essay workshops
Feedback on final exam (on scripts and one-to-one, as requested, with generic on-line feedback)

Reading list

Reading list for BIOCHEMISTRY - ENZYMES AND METABOLISM : http://aspire.surrey.ac.uk/modules/bms2035

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Biological Sciences BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biochemistry BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biotechnology BSc (Hons) 1 Optional A weighted aggregate mark of 40% is required to pass the module
Microbiology BSc (Hons) 1 Optional A weighted aggregate mark of 40% is required to pass the module
Veterinary Biosciences BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biomedical Science BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Microbiology (Medical) BSc (Hons) 1 Optional A weighted aggregate mark of 40% is required to pass the module
Biomedicine with Data Science BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biomedicine with Electronic Engineering BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.