ANALYTICAL AND CLINICAL BIOCHEMISTRY - 2017/8

Module code: BMS2043

Module provider

School of Biosciences and Medicine

Module Leader

THUMSER AE Dr (Biosc & Med)

Number of Credits

15

ECT Credits

7.5

Framework

FHEQ Level 5

JACs code

C700

Module cap (Maximum number of students)

N/A

Module Availability

Semester 2

Overall student workload

Independent Study Hours: 130

Lecture Hours: 28

Laboratory Hours: 10

Assessment pattern

Assessment type Unit of assessment Weighting
Practical based assessment PRACTICAL WRITE-UP 1 15%
Practical based assessment PRACTICAL WRITE-UP 2 15%
Examination EXAMINATION - MCQ QUESTIONS - 90 MINUTES 70%

Alternative Assessment

Practical reports, with data provided.

Prerequisites / Co-requisites

Pre-requisites: BMS1023 Chemistry and Maths for the Biosciences, BMS1041 Biochemistry: A Conceptual Overview, and BMS2035 Biochemistry - Enzymes and Metabolism In taking this module, you cannot in the same year take BMS2070.

Module overview

The Module will cover a range of topics that will address analytical techniques in research and clinical laboratories, as well as addressing the analysis of data and aspects of quality control.

Module aims

Provide an overview of analytical techniques used in research and clinical laboratories

Link taught topics to laboratory practicals

Use a blended learning approach to the teaching of Analytical Biochemistry by incorporating lectures, concept-directed tasks and tutorials

Develop a critical awareness of analytical techniques and the analysis/interpretation of data

Learning outcomes

Attributes Developed
Recognise analytical techniques that are commonly used in research and clinical laboratories KCT
Apply knowledge to the interpretation of data and reporting of results KCPT
Apply knowledge to specific tasks and problems as an independent learner KCPT
Demonstrate practical skills and interpret experimental results within the context of taught material. KCPT

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content

Indicative content includes:

 

Lectures:


Tools of Analytical Biochemistry
Analytical Standards and Sample Preparation
Spectroscopy: UV-Vis, fluorescence, luminescence, Infra-red
Chromatography (TLC, HPLC, GC, size exclusion, ion exchange, affinity)
SDS-PAGE, isoelectric focussing & western blotting
Factors affecting interpretation of clinical laboratory tests
Liver function tests (LFTs) and clinical cases
Lipoproteins
Lipids - clinical overview
Plasma proteins
Neonatal screening
Inherited metabolic diseases
Therapeutic drug monitoring
Point of Care Testing (POCT)
Evaluating Analytical Data (including overview of statistics: Regression, t-test, ANOVA)
Mass spectrometry


 

Practicals:


Urinalysis
Statistics (in silico)

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

• Develop critical thinking and analysis skills, related to the module content;
• Encourage discussion and participation in learning activities, related to the module content;
• Encourage independent learning.

The learning and teaching methods include:

• Lectures (3 hrs ¿ 10 weeks)
• Pre- & post-practical tutorials (1 hr ¿ 4)
• Pre-exam Tutorials
• Practicals (2 hrs ¿ 2 weeks)
• “Think - pair - share” class exercises
• “Elevator” class exercises
• SurreyLearn Discussion forum
• SurreyLearn on-line tests (MCQ)

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate:


The practical reports will assess Learning outcomes 1-4
The final exam will assess learning outcomes 1-4


 

Thus, the summative assessment for this module consists of:


Practical reports (2´15% weighting); deadline 1 week after practical
Final exam (70% weighting), which is MCQ-type questions (1.5 hrs; 90 questions)


 

Formative assessment and feedback


Feedback on practical reports
Pre-exam tutorial
MCQ questions on SurreyLearn
Use of “think-pair-share” and “Elevator” exercise during lectures

Reading list

Reading list for ANALYTICAL AND CLINICAL BIOCHEMISTRY : http://aspire.surrey.ac.uk/modules/bms2043

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.