ADVANCED TOPICS IN ANALYTICAL CHEMISTRY - 2017/8

Module code: CHEM028

Module provider

Chemistry

Module Leader

WARD NI Prof (Chemistry)

Number of Credits

15

ECT Credits

7.5

Framework

FHEQ Level 7

JACs code

F180

Module cap (Maximum number of students)

N/A

Module Availability

Semester 2

Overall student workload

Independent Study Hours: 116

Lecture Hours: 27

Laboratory Hours: 3

Assessment pattern

Assessment type Unit of assessment Weighting
Coursework COURSEWORK 30
Examination EXAM 2 HOURS 70

Alternative Assessment

Failure of the coursework unit of assessment will require the candidate to complete a data handling and publication coursework activity.

Prerequisites / Co-requisites

None.  

Module overview

Enhancing a knowledge and application of specialist topics in analytical chemistry including an awareness of the operation of advanced modern instruments with particular attention to the principles, practical aspects and problem solving/application aspects of advanced atomic spectroscopy, chromatography, electrochemistry and mass spectrometry. Special attention on research applications of advanced instrumental methods.

Module aims

To describe and evaluate the fundamentals of advanced instrumental methods, with particular emphasis on recent developments and research applications

To describe and evaluate the principles, instrumentation, problem solving and practical aspects of advanced atomic spectroscopy, chromatography, electrochemistry, ion beam analysis and mass spectrometry

To reflect and improve the students awareness of advanced quality control and its application in analytical chemistry.

To improve the students awareness of measurement, the use of statistics and calculations for quantitative analysis and journal publication as used in research.

Learning outcomes

Attributes Developed
Understand and critically evaluate the relative usefulness of a range of analytical techniques, including advanced atomic spectroscopy, hyphenated techniques using mass spectrometry (HPLC-ICP-MS, HPLC-MS, GC-MS), electrochemistry and sensors, ion beam analysis;
Critically evaluate the operation of modern instrumental techniques coupled with an appreciation of instrumental calibration, validation, problem solving, data handling and good laboratory practice; and
Critically evaluate instrumental interferences (identification and practical solution) and key analytical parameters (detection limit, linear dynamic range, sensitivity, levels of accuracy and precision)
Conceptually understand and critically evaluate the use of statistics in a research environment (correlation analysis, calculation of least squares line of best fit and dilution factors in quantitative analysis), principle component analysis, linear discriminant analysis)

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content

Indicative content includes:



review of recent advances in modern analytical techniques; inductively coupled plasma atomic emission spectrometry; inductively coupled plasma mass spectroscopy (ICP-MS) - principles, instrumentation, interferences and operation, laser ablation, electrothermal vaporisation; speciation analysis using hyphenated-mass spectrometry techniques (applications for As and Hg speciation); instrumental neutron activation analysis (INAA); mass spectrometry sample introduction (ES), time-of-flight, quadrupole to sec (MS-MS)


electrochemistry – amperometric enzyme-based biosenors, methods and applications; surface sensor techniques (QCM and SPR); permselective membranes – small molecule speciation; nanoselective materials – large biomolecule speciation; recent research applications of nanosensors


review X-ray fluorescence spectroscopy (XRF), Statistics: application of calibration curves (including use of dilution factors), and


review of separation science (GC and HPLC); method development, optimisation, choice of method; preparative chromatography, SFC, counter-current, HILIC, chiral separations, role of HPLC/GC in pharmaceutical, biomedical and environmental analysis with a review of recent advances in applications.



 

Methods of Teaching / Learning

The learning and teaching strategy is designed to build on skills gained in FHEQ 5 (CHE2030):



develop a knowledge of the fundamentals and operation of advanced modern analytical instruments;


develop a practical approach to good laboratory practice and quality control in the research laboratory; and


enhance data handling, statistical analysis and analytical publication report writing (The Analyst).



 

The learning and teaching methods include:



individual data handling and analytical publication report (coursework);


instrumental operation and problem solving/applied resaerch  (chromatography, atomic spectroscopy, nuclear anallysis, and electrochemistry).



 

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate sufficient theoretical and applied practical skills of the above.

Thus, the summative assessment for this module consists of:


data handling and analytical publication (The Analyst) 30%
examination 70%.


 

Formative assessment

Commentary and feedback on coursework and informal tutorials.

 

Feedback

Verbal throughout the ICP-MS practical and data handling session, and subsequent written feedback on the submitted Excel data file and Analyst publication (coursework).

 

Reading list

Reading list for ADVANCED TOPICS IN ANALYTICAL CHEMISTRY : http://aspire.surrey.ac.uk/modules/chem028

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Chemistry with Forensic Investigation MChem 2 Compulsory A weighted aggregate mark of 50% is required to pass the module
Chemistry MChem 2 Optional A weighted aggregate mark of 50% is required to pass the module
Chemistry MRes 2 Optional A weighted aggregate mark of 50% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.